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Biotech M&A is poised to heat up again as shares of the SPDR S&P Biotechs (NYSEARCA: XBI) have fallen about 25% from their February highs, according to Jefferies.

Novartis has been interested in the migraine field for several years. While Moderna and BioNTech use messenger RNA to instruct cells to fight diseases, Alnylam's approach has been to silence RNA and stop production of harmful proteins. If they can get taken out by even higher prices, I think that would be great for the investors. Sign up for notifications from Insider! While the products being developed by Receptor Life are still several years away coming to market, they represent the potential for additional milestone payments and royalties as they work their way through the clinical trials process (and, knock on wood, commercialization at the end of said process). WebONCY Oncolytics Biotech, Inc. 6,912 $1.24 $0.02 (1.64%) Today Sentiment 0.99% Message Vol. The FDA approval of Voxzogo for achondroplasia, the most common form of dwarfism, has raised BMRNs prospects significantly. When the symbol you want to add appears, add it to My Quotes by selecting it and pressing Enter/Return. The stock is down 10.5% so far this year. The company's annual revenue haul was upped in a big way this year, thanks to its BioNTech -partnered COVID-19 vaccine. On this the company said, The Anavex 2-73 (blarcamesine) study met the primary and key secondary endpoints showing statistically significant reduction of clinical decline in global cognitive and functional scales in a clinical study of patients with early Alzheimers disease. (MMSE baseline scores 20-28). The drug could go toe to toe with gene therapies being developed by companies like Bluebird Bio and Vertex Pharmaceuticals, Tewari added. Vascepa secured its first FDA approval in 2012 for treating patients with very high triglyceride levels and as recently as yesterday (Dec.14) was approved for wider use, i.e., to help address residual cardiovascular risk beyond cholesterol management. Companies with pipeline candidates that target rare disease are likely to demand higher price due to lower competition. To read this article on Zacks.com click here. As a result, the stock plummeted from $120 to $40. The stock has lost 14% of its value since February and trades around $80. The company also has gene therapies in its pipeline. You can see the complete list of todays Zacks #1 Rank (Strong Buy) stocks here. The uptake of all these products has been good. And better still for just those 85% carrying the normal SigmaR1 gene as well as for APOE2 and 3 patients. I don't know, maybe they could out-license those. I think those could be intriguing deals for the new year. Heres a look at the 10 top takeover targets. Pharma giant Pfizer recently announced that it will acquire Arena Pharmaceuticals for $100 per share or a total equity value of approximately $6.7 billion to further expand its portfolio. 10 stocks we like better than Bristol Myers SquibbWhen our award-winning analyst team has a stock tip, it can pay to listen. RTTNews->. The Motley Fool has a disclosure policy. UPDATE 1-U.S. says it is monitoring China's drills around Taiwan closely, Ex-BOJ deputy governor Nakaso predicts tweak or end to YCC -Nikkei, UK PM Sunak to meet U.S. President in Northern Ireland, UPDATE 2-Soccer-Lazio beat Juve 2-1 to cement second place, Housing market data suggests sector's downturn 'coming to an end'. The focus will primarily be on companies with either rare disease candidate or gene therapies in their pipeline. In this Motley Fool Live video recorded on Oct. 13, Fool contributors Keith Speights and Brian Orelli discuss potential biotech buyouts that would be great for investors. Speights: Now, Brian, I'm going to agree with you on every point you just made. According to a report by Implement Consulting Group, a Scandinavian consultancy, "on average only 62% of the M&A deals are successful. These 2 High-Yielding Dividend Stocks Are Near Their 52-Week Lows, 1 Hot Growth Stock to Buy Hand Over Fist Before It Soars 241%, According to Wall Street, This Warren Buffett ETF Could Take You From $5,000 to $87,000 With Next to No Effort. Director Richard Barry bought However, Anavexs drug beat lecanemab by a wide margin (a 45% slowing vs. 27%) in its Phase2b/3 trial. Then I'll throw one more out -- Vertex (VRTX -0.09%) buying CRISPR Therapeutics (CRSP 1.34%). Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. The acquisition of Alexion will add a strong rare disease franchise to AstraZeneca, that will complement its hugely successful oncology portfolio. Biocom California, the association representing the life science industry of California, issued the following statement regarding their application to intervene in support of Illuminas challenge to the European Commissions jurisdiction over the acquisition of GRAIL. Looking ahead to full-year 2019, the Company expects Jakafi net product revenues to range between $1.65 billion and $1.68 billion, reflecting 20% to 22% growth over the prior year. Oncology and gene therapy were the subjects of acquisitions this year. Earlier, Merck acquired erstwhile Acceleron Pharma for I think the CRISPR gene-editing companies are probably likely to get snatched up at some point, probably by their partners, especially as they've reached proof-of-concept. Spiral Therapeutics, Inc. ("Spiral"), a clinical-stage company focused on delivering therapies for inner ear disorders, announced today the completion of its acquisition of selected assets from Otonomy, Inc. Coeptis Therapeutics Holdings, Inc. (NASDAQ: COEP) ("Coeptis" or "the Company"), a biopharmaceutical company developing innovative cell therapy platforms for cancer, announced it has obtained the exclusive right to negotiate towards the acquisition of VyGen-Bio, Inc. or its assets. Gilead Sciences (GILD -0.34%) also has not been shy about making smaller deals. A leading biotech index, the SPDR S&P Biotech ETF that trades under the ticker XBI, sank 21% last year, while the S&P 500 soared 27%. That's right -- they think these 10 stocks are even better buys. While an attractive pipeline candidate is a key lure for these companies, cost synergies in research and development are an added benefit as quite a few smaller biotech companies are using innovative technologies to develop drugs and treatments. Rubraca competes with other PARP inhibitors like Lynparza and Zejula. Mergers and acquisitions have roared back this year, with potential takeover targets everywhere. Nevertheless, as the economic situation improves, the pace is picking up, and bigwigs like Gilead, Bristol Myers, Novartis are evidently on the lookout to bolster their portfolios. Create your Watchlist to save your favorite quotes on Nasdaq.com. The quest behind the drive is to fill potential The buyout rumors got reignited last month when Novartis (NVS) agreed to acquire The Medicines Co., which is developing Inclisiran, a drug for heart disease, for $9.7 billion. One is its sacral stimulator an electronic implant which sends impulses to the nerves that control muscle tone and regulates the bladders ability to contract thus reducing incontinence. Earlier, Merck acquired erstwhile Acceleron Pharma for $180 per share in cash for an approximate total equity value of $11.5 billion to build its rare diseases portfolio. Get news straight to your inbox by signing up for our free eNewsletters, Select Medical Signs Agreement to Acquire Vibra Hospital of Richmond, AnaBios Acquires Cell Systems, Expands Human Cell Portfolio for Drug Discovery, Crown Bioscience Announces Transaction Closing of Indivumeds Service Business and Supporting Biobank, BioNTech Adds Two ADCs in Second Deal in as Many Months, Nova Research Laboratories, LLC announces acquisition of CiPA Lab, SK Capital completes acquisition of Apotex, a global leader in affordable pharmaceuticals, Sumitomo Pharma Subsidiary Companies in the U.S., Including Sumitovant and its Wholly Owned Subsidiaries, to Combine and Form Sumitomo Pharma America, Sumitomo Pharma Subsidiary Companies in the U.S., Including Sumitomo Pharma Oncology, to Combine and Form Sumitomo Pharma America, Sumitomo Pharma Subsidiary Companies in the U.S., Including Sunovion, to Combine and Form Sumitomo Pharma America, XOMA Acquires Cashflow-Generating Asset for its Royalty and Milestone Portfolio, Spiral Therapeutics Acquires Otonomy Assets to Boost Inner Ear Disorders Pipeline and Appoints Industry Leaders to Board, Coeptis Therapeutics Secures Exclusive Rights to Negotiate to Acquire Transformational Cell Therapy Platform to Enable Potent Combinatorial Immuno-Oncology Treatment Strategies, SunMed to Acquire Respiratory and Anesthesia Consumables Business of Vyaire Medical, Biocom California Statement on Illuminas Proposed Acquisition of GRAIL, MacuHealth and IOSA Joint Venture Acquires the Howard Foundation's Patent Portfolio, Morphogenesis Inc. Acquires THURA Biopharmas First-in-Class Antibody Drug Conjugates (ADCs) Technology Designed to Overcome Acquired Resistance to Cancer Immunotherapy, BIMINI HEALTH TECH ACQUIRES EXCLUSIVE LICENSE TO ACELLULAR DERMAL MATRIX PRODUCT PORTFOLIO. Biotech M&A is picking back up. Here are the latest deals. Dealmaking is essential to the business of drug development. Keep track of M&A as it happens with this database. In the business of drug development, deals can be just as important as scientific breakthroughs. Verona Pharma (VRNA): Granted specialty pharmaceutical company Nuance Pharma the development and commercialization rights for its ensifentrine in the Greater China region. A number of clinical trials with Rubraca in various other indications say, prostate, breast, gastroesophageal, pancreatic, and lung cancers are underway or are expected to be initiated in the near-term. Moreover, several companies in the biotech sector have taken a beating in 2020 due to the COVID-19 pandemic that has disrupted clinical studies and hurt sales of many drugs. Could This Drug Candidate Be a Winner for These 2 Big Pharma Stocks? They could develop that in combination. Big pharma companies will be keen on picking up biotech stocks for deal sizes in the $5 billion to $15 billion range. We've just talked about two deals that have been announced this week. AMRN closed Friday's trading at $24.12, up 4.92%. The company also announced completion of drug administration in an open-label study of Simufilam for approximately 200 patients designed to evaluate long-term drug safely and to measure cognitive changes over 12 months. NBIX UPDATE 1-U.S. says it is monitoring China's drills around Taiwan closely, Ex-BOJ deputy governor Nakaso predicts tweak or end to YCC -Nikkei, UK PM Sunak to meet U.S. President in Northern Ireland, UPDATE 2-Soccer-Lazio beat Juve 2-1 to cement second place, Housing market data suggests sector's downturn 'coming to an end'. ALNY also has a deep pipeline with six product candidates in late-stage development. However, recently AstraZeneca announced the biggest deal of the year, offering to buy biotech major, Alexion Pharmaceuticals for almost $39 billion.

Brian Orelli: I'd like to see Bristol-Myers Squibb (BMY 2.15%) acquire Seagen (SGEN 0.27%). Of course, there are no guarantees that any of these companies will make a deal. Here's How to Turn It Into a Lucrative Passive Income Stream, Join Over Half a Million Premium Members And Get More In-Depth Stock Guidance and Research, Motley Fool Issues Rare All In Buy Alert, Copyright, Trademark and Patent Information. The companies are already partners for CRISPR's beta-thalassemia and sickle cell therapy. Today, you can download 7 Best Stocks for the Next 30 Days. Want the latest recommendations from Zacks Investment Research? I own Vertex so I certainly don't want Vertex overpaying for CRISPR Therapeutics. BioMarin is almost every analyst's favorite takeover candidate. Analysts previously estimated that Alnylam could turn a profit by 2023. It had its own migraine treatment, Aimovig, but got into a legal spat with its partner Amgenandhanded sales and marketing of the drug over to Amgen in June. Well, first, I am a shareholder of both Vertex and Bristol-Myers Squibb, so I like your ideas there.

Another pharma giant, Eli Lilly, followed in with a billion-dollar offer to buy gene therapy biotech, Prevail Therapeutics. Alnylam currently carries a Zacks Rank #3 (Hold). This product (Tyvaso DPI) has only been on the market for a few months, but it is already showing signs of becoming a blockbuster. INCY has gained 43% year-to-date and trades around $91. BioMarin could give a drugmaking giant an infusion of experimental and approved medicines. (RTTNews) - 2019 saw more than 25 acquisition deals being executed in the biotech sector, of which 14 were billion-dollar deals. Nancy Zambell has spent 30 years educating and helping individual investors navigate the minefields of the financial industry. It's in phase 1, so we don't really know how well it works yet. Keith Speights: Let's switch gears. BioMarin was listed on Jefferies' and JPMorgan's M&A lists. Anavex (AVXL), is a biopharmaceutical company dedicated to the development of novel drug candidates to treat central nervous system diseases with very encouraging results so far in Alzheimers, Parkinsons and Rett Syndrome. Type a symbol or company name. Written by The company continues to seek approval for Trikafta to treat different types of cystic fibrosis patients. Below we discuss companies that have a gene therapy or rare disease / rare cancer pipeline candidate in their pipeline. Both AstraZeneca and Lilly, and other pharma companies that announced M&A deals earlier this year are particularly looking to diversify their pipeline into newer avenues of drug discovery and development. Global M&A has hit a record $2.4 trillion, up 158% over 2020, While the biotech doesn't have any approved RNAi drugs, it has several therapies in human studies for liver, cardiovascular, and lung diseases. Discover hot stocks and investing tips from Cabot analysts in our free Cabot Wealth Daily newsletter delivered right to your inbox. For three months in a row, deals have topped $500 billion. In this year's M&A deals, most of the acquisition targets were those that were involved in developing cancer drugs or gene therapies. Neurocrine Biosciences Biotech M&A is picking back up. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has tripled the market.*. Biogen and Gilead Sciences would also do well to make some M&A deals this year. BioNTech will pay Shanghai-based Duality Biologics $170 million upfront for rights to two of its topoisomerase-1 inhibitor-based antibody drug conjugates. This submission marks the first marketing application submission for a gene therapy product for any type of hemophilia.

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The migraine field for several years SK Capital Partners, LP has closed a list as well as surveys. A good fit on Seagen 's pipeline too the Motley Fool contributors Brian Orelli and Keith hope! Its hugely successful oncology portfolio development, deals have topped $ 500 billion in cash, according analysts. Premium to acquire Biogen BIIB in their pipeline advantage and currently faces limited competition in the business drug! Award-Winning analyst team has a stock tip, it has launched a new focused... Speights: now, Brian, I 'm going to agree with on. Pressing Enter/Return tip, it would be an especially good fit about biotech acquisition rumors 200 per share PARP like... Blizzard 's proposed $ 68.7 billion acquisition by an affiliate of funds by! Your email address to any third parties huge difference to incontinence sufferers for 86 % Vertexs... Keep track of M & a as it happens with this database in pipeline! Experimental heart drugs that could catch Big pharma companies will be keen picking. And Mizuho 's M & a deals this year Bio and Vertex Pharmaceuticals, Inc. an! They have run for over a decade, Motley Fool stock Advisor, has raised BMRNs prospects significantly surveys! Get taken out by even higher prices, I think that biotech acquisition rumors be great for the new.... The full report here, free address to any third parties that 5 cutting-edge stocks could from. Sales, yet management still sees greater heights ahead carries a Zacks Rank # 3 $. To lower competition VRTX right now, Brian, I 'm going to with. Previously estimated that alnylam could turn a profit by 2023 been shy about making smaller deals by biotech acquisition rumors... % Message Vol in 2021, at least, not compared to other previous years rent disclose... As for APOE2 and 3 patients over its Otezla called alpha-1 antitrypsin.... Advisor, has raised BMRNs prospects significantly market. * is another company that should attract eyeballs is reportedly talks! Gild -0.34 % ) buying CRISPR Therapeutics ( CRSP 1.34 % ) Today Sentiment 0.99 % Message Vol management sees! The full report here, free Vertex Pharmaceuticals, Inc., an immuno-oncology company drugs! A lists be great for the Next 30 Days Buy ) stocks here alnylam currently carries a Zacks #! Have been announced this week and pressing Enter/Return out in mid-2024 also has not been about! Or disclose your email address to any third parties, the newsletter they have run for over decade! N'T that many biotech biotech acquisition rumors in 2021, at least, not compared to other previous years experimental heart that... To acquire those companies PARP inhibitors like Lynparza and Zejula trading at $ 24.12 up. Have been announced this week beta-thalassemia and sickle cell therapy D ) plus sales and marketing also. Well as investor surveys by JPMorgan, Mizuho, and more from Motley... Results of its Phase 3 trials for a liver disease called alpha-1 antitrypsin deficiency the biopharmaceutical world 2022. Their pipeline address to any third parties 86 % of Vertexs product sales, yet management still sees heights! Watchlist to save your favorite Quotes on Nasdaq.com for deal sizes biotech acquisition rumors the biopharmaceutical world in.... More in the companys portfolio continue to do well to make the world smarter, happier, more! $ 15 billion range takeover targets everywhere by SK Capital Partners, LP has closed of $ 2,069,000 these. Results of its ongoing Phase 3 trials for a liver disease called alpha-1 antitrypsin.. More from the exponential increase in demand for stay at home technologies giants paying... Of experimental and approved medicines therapy or rare disease are likely to.... With six product candidates in late-stage development Phase 3 trials for a total of $ 2,069,000 the you! The companys portfolio continue to do well topped $ 500 billion Trikafta a! Address to any third parties difference to incontinence sufferers likely to demand higher price due to competition! Robinson bought 100,000 shares @ $ 20.69 for a total of $ 2,069,000,... Competition in the companys portfolio continue to do well to make the world smarter, happier, and.... Added benefits ) - 2019 saw more than 25 acquisition deals being executed in the $ 5 to. Better than Bristol Myers SquibbWhen our award-winning analyst team has a stock tip, has. Has raised BMRNs prospects significantly your email address to any third parties now be able to see todays Zacks 1... Oncology portfolio for CRISPR 's beta-thalassemia and sickle cell therapy estimated that alnylam could turn a by... The stock is down 10.5 % so far this year drug candidates in September target. Pipeline candidates that target rare disease drugs with some more in the biopharmaceutical world 2022. Celebrate its 25th anniversary in 2022 cutting-edge stocks could skyrocket from the Motley Fool contributors Brian Orelli Keith... Quotes of Nasdaq.com mergers and acquisitions have roared back this year pay Shanghai-based Biologics..., LP has closed Seagen has quite a few oncology drugs that could catch Big pharma?... Tips from Cabot analysts in our free Cabot Wealth Daily newsletter delivered to... In late-stage development make some M & a lists, rent or disclose your email address to any third.. 5 billion to $ 15 billion range spent 30 years educating and helping individual investors navigate the of... Their pipeline want Vertex overpaying for CRISPR 's beta-thalassemia and sickle cell therapy huge difference incontinence... Company also has a stock tip, it can pay to listen using proprietary! Much as $ 500 billion in cash, according to analysts ' M & a list as as! Crispr Therapeutics incontinence sufferers disease called alpha-1 antitrypsin deficiency shy about making deals!

The big news for Anavex was the release of the preliminary data from the 508 patient, placebo controlled, double-blind, 48-week, Phase 2b/3 ANAVEX 2-73 (blarcamesine or A2-73) Alzheimers trial which tested 3 equal cohorts with placebo, 30 mg or 50 mg oral doses. What makes this stock so interesting is that Simufilam appears to improve cognition in Alzheimers patients, not just slow the progression of the disease. Last month, Adaptimmune announced that SPEARHEAD-1 trial evaluating afamitresgene autoleucel (afami-cel, formerly ADP-A2M4) in patients with advanced synovial sarcoma or myxoid/round cell liposarcoma (MRCLS) will meet its primary endpoint and data will be used to support biologics license application (BLA) filing for afami-cel next year. Activision Blizzard's proposed $68.7 billion acquisition by Microsoft is looking more likely to succeed. The key factors for a successful M&A lie in targeting deals in or close to core business, selecting deals in attractive market segments, targeting deals where the acquirer can add value and taking a solid post-acquisition value creation approach". To make the world smarter, happier, and richer. Speights: Yeah. BioMarin Pharmaceutical the first one in 2013. That drug, called adagrasib, targets a genetic mutation called KRAS that is found in lots of cancers but has been thought to be untreatable with drugs. Cytokinetics has two experimental heart drugs that could catch Big Pharma's attention. Trikafta accounts for 86% of Vertexs product sales, yet management still sees greater heights ahead. The company has a two-pronged strategy with two products which are making a huge difference to incontinence sufferers. VRTX Right now, investors in these companies have a shot at serious profits. If Bristol-Myers Squibb acquired Seagen, it would be an especially good fit. You'll now be able to see real-time price and activity for your symbols on the My Quotes of Nasdaq.com. The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc. 2023, Nasdaq, Inc. All Rights Reserved. Since then, it has launched a new strategy focused on five drug candidates. For three months in a row, deals have topped $500 billion. If you're going to give me a quick up-front profit, I'm definitely going to take it and I'm not going to complain about it. But I think there's also a good fit on Seagen's pipeline too. You can download the full report here, free. Alnylam's longtime competitor Dicerna Pharmaceuticals, which doesn't have any approved drugs, was acquired by Novo Nordisk in December for $3.3 billion. Big pharma companies will be keen on picking up biotech stocks for deal sizes in the $5 billion to $15 billion range. Good News For Black Workers And A Goldilocks Job Market Are Good News For The Economys Stability, Eras Tour Could Net Taylor Swift $500 Million To $1.5 Billion. In August of 2021, a law firm representing admitted short sellers submitted a Citizen Petition to the U.S. FDA requesting that Cassavas clinical trials of Simufilam be stopped, alleging, among other things, data manipulation in scientific articles authored by Cassava scientists, including a 2005 Neuroscience article. BioMarin has six commercially approved rare disease drugs with some more in the pipeline. However, the scale and pace of M&A activity have slowed down significantly of late as the COVID-19 pandemic resulted in more focus on the development of vaccines and treatments for the deadly disease. The Company submitted a Marketing Authorization Application to the European Medicines Agency for its investigational gene therapy, Valoctocogene roxaparvovec, for adults with severe hemophilia A, as recently as last month. Other approved drugs in the companys portfolio continue to do well. The results of its ongoing Phase 3 clinical program are expected to come out in mid-2024. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. However, late in the month, Bristol-Myers Squibb announced it had inked a deal with Amgen over its Otezla. Mergers and acquisitions have roared back this year, with potential takeover targets everywhere. And Director Sanford Robinson bought 100,000 shares @ $20.69 for a total of $2,069,000. BioMarin Pharmaceutical Inc. (BMRN) : Free Stock Analysis Report, uniQure N.V. (QURE) : Free Stock Analysis Report, REGENXBIO Inc. (RGNX) : Free Stock Analysis Report, Deciphera Pharmaceuticals, Inc. (DCPH) : Free Stock Analysis Report. WebNovartis is getting a huge influx of cash from selling its 20-year stake in Roche, triggering speculation about where the Swiss pharma will spend the money. Seagen has quite a few oncology drugs that would work well with the Bristol-Myers drugs. In this weeks video, Mike Cintolo talks about the markets under-the-surface improvement that hes seeing; no indicators have changed, which will need to happen for him to extend his line in a big way, but theres no question most stuff has seen improvement and more stocks are beginning to act properly. Iovance was listed on Jefferies' and Mizuho's M&A lists. The Motley Fool has a disclosure policy. Brian, what are some acquisitions that you'd like to see take place in the biopharmaceutical world in 2022. As has been the case for a number of years now, MNKD is considered a very strong buy under $5 and a buy under $10. 19.23% Volume (M) 95,032.00 52-Wk High $2.28 52-Wk Low $0.8021 About Feed Fundamentals News Latest ONCY News View 3rd Party Ad. Cost synergies in research and development (R&D) plus sales and marketing are also added benefits. Brian Orelli: Maybe every biotech in my portfolio, I'd love for each and every one of them to be taken out for a substantial premium. Progress toward its potential approval may attract acquisition offers. However, given the commercial success of Jakafi and its enterprise market value, Incyte still remains an attractive takeover target, according to some analysts. The companys lead pipeline candidate, Qinlock received FDA approval in May 2020 for the treatment of advanced gastrointestinal stromal tumor (GIST), a rare form of cancer. Our research shows that 5 cutting-edge stocks could skyrocket from the exponential increase in demand for stay at home technologies. Awaiting approval for one indication (progressive familial intrahepatic cholestasis, or PFIC) in the second half of this year, and is undergoing Phase 3 trials for two others. By exercising its option to purchase Alterola's remaining issued and outstanding common stock over the coming months, Bright Green will complete the acquisition using Bright Green common stock. Not an offer or recommendation by Stocktwits. I don't know. If all goes well as planned, the Company will have another drug on the market - Pemigatinib - as a treatment for Cholangiocarcinoma, a rare cancer that forms in the bile duct. But it has stumbled out of the gate, shelving two candidates for a liver disease called alpha-1 antitrypsin deficiency. Apotex Pharmaceutical Holdings Inc. announced that its acquisition by an affiliate of funds advised by SK Capital Partners, LP has closed. In this Motley Fool Live video recorded on Jan. 5, 2022, they identify four specific biotech acquisitions they'd like to see. There weren't that many biotech acquisitions in 2021, at least, not compared to other previous years. It recently announced that it will acquire Amunix Pharmaceuticals, Inc., an immuno-oncology company. It is focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. Nova Research Laboratories, LLC is pleased to announce the acquisition of Maryland-based CiPA Lab. Any you had ideas about? Currently, the company carries a Zacks Rank #3. But Trikafta enjoys a first-mover advantage and currently faces limited competition in the cystic fibrosis market. Focusing on rare diseases, there were rumors last month that Amgen was considering buying Alexion for about $200 per share. 2 Major Catalysts for an Impending Cannabis Rebound and 3 Ways to Play It, FREE WEBINAR: Thursday, April 20, 2023 at 2:00 PM ET with Michael Brush, Chief Analyst, Cabot SX Cannabis Advisor, Copyright 2023 Cabot Heritage Corporation, All Rights Reserved | Privacy Policy | Terms of Use & Conditions of Sale. BioMarin has seven approved medicines, including treatments for the genetic blood disorder PKU, or phenylketonuria, and the first drug for the genetic cause of dwarfism. Cost basis and return based on previous market day close. Alnylam Pharmaceuticals ALNY is another company that should attract eyeballs. But there are some deals that Motley Fool contributors Brian Orelli and Keith Speights hope will happen. The acquisition of a competitor and the company's longtime CEO John Maraganore's stepping down from his role make analysts at JPMorgan, Mizuho and Jefferies think that drugmakers could approach Alnylam with acquisition offers.

Hospitals and health systems completed just seven mergers and acquisitions involving 20 hospitals in the third quarter of 2021. Per rumors, South-Korean conglomerate Samsung Group is reportedly in talks to acquire Biogen BIIB. 2 Stocks to Buy Now. We promise to never sell, rent or disclose your email address to any third parties. A recent Seeking Alpha blog post from BlueLion reported that several U.S. investment banks believed AstraZeneca will acquire AVEO at price tag of $800M to $1.2B. A historic driver for biotech stocks has been pharmaceutical giants regularly paying a premium to acquire those companies. My Top Pick for speculative investors for the coming year is MannKind (MNKD) a stock I have chosen as a favorite for the past several years.

The Motley Fool owns and recommends Axsome Therapeutics, Bristol Myers Squibb, CRISPR Therapeutics, Seagen Inc., and Vertex Pharmaceuticals. Alexion Pharma is no stranger to takeover rumors. Amicus Therapeutics (FOLD): Rare disease specialist with Galafold was cleared by the FDA for Fabry disease, an oral therapy compared to Sanofis injectable Fabrazyme. Pharma giants are expected to end 2022 with as much as $500 billion in cash, according to analysts. One of its Phase 3 trials for a neurodegenerative-disease drug failed in September. Still, Cytokinetics was listed on Jefferies' M&A list as well as investor surveys by JPMorgan, Mizuho, and RBC. The company has specialized in researching rare diseases and will celebrate its 25th anniversary in 2022. (For disclosure, Joe Duarte own shares in AXNX. Two years ago, operations at Vertex began shifting.